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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3851637d4054d0b3784a2dfe6ae485f915b8c2a5992cacc6e505c0d3345996bd' 
  AND token = 'dx+1k/5DTcwZW120VieT3DyVGSTnsYMUmvLMQklcXrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}