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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2bb96a20d135798023c6e5b9b85be2bd51a92570e89cc8fcb4c9df32df4376' 
  AND token = 'T6bTQGdcPRsHmUV2Z65BszkrwCbadfaFn/Gw7MvXOrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}