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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a21409aa653648476888ef88b1fc15641b3856b3842ccc42ae791c7ea2243bf6' 
  AND token = 'yQGKVlyY+7/3BOy0BWWrSfMtDYXaKaAl471sAQuCSHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00122

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}