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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f754e5c4a1453300e7853cb58c9bccb53f918335307abfa911105a1ecde339' 
  AND token = 'w2pfow3ydcUEhFQaiYEiwNlqEKO2n5TRH68HnxO++E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}