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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e77351b33a4c1c7fc9341d2e3cae68abe839cb66126ba4ebcc46e5030d0339f8' 
  AND token = 'Ya1TlCkEZtz1ugUR2Tmup3A5XzK8ZGdDFARq3XUMjVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}