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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a62ec8aea8f787e846faf5b11672dde8b2aca2e445591a4764284d9773f2a0cf' 
  AND token = 'B4bl45SJhytRL9Dc6TqPjvQhxjoAMRQFkqGp81NZyMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}