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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cb01fe1565eb264afa69284e883ed2b0d26403880351ac6e8163ea45480e447' 
  AND token = 'Fw9F6Wl2ZIHltuegm//3SBQkGwDbGKj9P8vWH5syXY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}