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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02a42221d0cef8a53297b305f5d7320b6efe957fddf34d0049c116ea5ffc141c' 
  AND token = 'aZtVGHdM1plJNKC6QWLvrpEgxPNSNYFMHUHAyNwy+Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}