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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00734700f009d569cf949d762dbcee4327ad58cd3d501381e2a591374245d161' 
  AND token = 'o1CSpY5ZlNzDERL3x1InBHAaajnMYbRAd+t7SQhd2yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00119

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}