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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd61256983a3d9d5a37f09d6dead021aeabd9cdc34a03654e0fa768176a728ea1' 
  AND token = 'XBewzvyABzaydI4eh+TeNnhDuIzr8mEWG4PV0Z6X0jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}