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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f33879b3b1165c733e252861ed911491a682d4f97b6c8c53ab5bf716609d5c6' 
  AND token = 'p4A5kY3EERAFoJbH96qAsCoz1eEqzOLhg0HOql+CcfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}