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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4350ec5e4a19e1dd637e3ee56d27dced0f4d153838bc31456bb341876f996446' 
  AND token = 'QGmDkDJ49rbfut2+8FvgJ7GdJW8iOoSWnXs0dpCI4Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}