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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f457fff74108160ac54f1ad6fcc590df2f108fb2665018fcdbe1573383f8aab' 
  AND token = 'Kra+/Zhy+CWv8J/O/kr689vNsKJTZN28RZO2UMNbPpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}