SELECT 
  pfv.feature_id, 
  pfv.product_id, 
  pfv.variant_id, 
  gp.group_id 
FROM 
  cscart_product_features_values AS pfv 
  INNER JOIN cscart_product_variation_group_products AS gp ON pfv.product_id = gp.product_id 
  INNER JOIN cscart_product_variation_group_features AS gpf ON gpf.group_id = gp.group_id 
  AND gpf.feature_id = pfv.feature_id 
WHERE 
  pfv.lang_code = 'en' 
  AND gp.group_id IN (
    45, 340, 273, 66, 219, 175, 289, 284, 236, 
    349, 161, 293, 272, 158, 231, 307
  )

Query time 0.00228

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "44.81"
    },
    "nested_loop": [
      {
        "table": {
          "table_name": "gpf",
          "access_type": "range",
          "possible_keys": [
            "PRIMARY",
            "idx_group_id"
          ],
          "key": "idx_group_id",
          "used_key_parts": [
            "group_id"
          ],
          "key_length": "3",
          "rows_examined_per_scan": 16,
          "rows_produced_per_join": 16,
          "filtered": "100.00",
          "index_condition": "(`softwarepirmam_hewadelivard_cscart_4`.`gpf`.`group_id` in (45,340,273,66,219,175,289,284,236,349,161,293,272,158,231,307))",
          "cost_info": {
            "read_cost": "9.61",
            "eval_cost": "1.60",
            "prefix_cost": "11.21",
            "data_read_per_join": "1K"
          },
          "used_columns": [
            "feature_id",
            "group_id"
          ]
        }
      },
      {
        "table": {
          "table_name": "gp",
          "access_type": "ref",
          "possible_keys": [
            "PRIMARY",
            "idx_group_id"
          ],
          "key": "idx_group_id",
          "used_key_parts": [
            "group_id"
          ],
          "key_length": "3",
          "ref": [
            "softwarepirmam_hewadelivard_cscart_4.gpf.group_id"
          ],
          "rows_examined_per_scan": 3,
          "rows_produced_per_join": 48,
          "filtered": "100.00",
          "cost_info": {
            "read_cost": "12.00",
            "eval_cost": "4.80",
            "prefix_cost": "28.01",
            "data_read_per_join": "768"
          },
          "used_columns": [
            "product_id",
            "group_id"
          ]
        }
      },
      {
        "table": {
          "table_name": "pfv",
          "access_type": "ref",
          "possible_keys": [
            "PRIMARY",
            "fl",
            "lang_code",
            "product_id",
            "fpl",
            "idx_product_feature_variant_id"
          ],
          "key": "fpl",
          "used_key_parts": [
            "feature_id",
            "product_id",
            "lang_code"
          ],
          "key_length": "12",
          "ref": [
            "softwarepirmam_hewadelivard_cscart_4.gpf.feature_id",
            "softwarepirmam_hewadelivard_cscart_4.gp.product_id",
            "const"
          ],
          "rows_examined_per_scan": 1,
          "rows_produced_per_join": 48,
          "filtered": "100.00",
          "cost_info": {
            "read_cost": "12.00",
            "eval_cost": "4.80",
            "prefix_cost": "44.81",
            "data_read_per_join": "37K"
          },
          "used_columns": [
            "feature_id",
            "product_id",
            "variant_id",
            "lang_code"
          ]
        }
      }
    ]
  }
}