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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b74f529cebddea0c481af577d8a675d7b8b1999ef247bbcf042ee5df7c976a3' 
  AND token = 'eB1Xa9VTZ4wuSdLNO3bO+mcGLckO9kHZDYY+3anOwxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}