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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c29d0bbd2e6c0c7aed8959ac6954324ccf82472329422b60409adf95e2e737d' 
  AND token = 'DDZ2OzkOHyo3pvYhUwq6tiqqwSr2XGR5FhAy1u9YXwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}