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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88cd661f74ce7cfc3f5dbac4a1265ee75eb49ac9ea7ae64188796378a341104a' 
  AND token = 'XOH9LY5YetP3Ort96ikZsNb1KLaYM0VjUcjyUWoz0+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}