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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32223a9e00eae2906cdca0d0e4fa6c189c1a8344ea292df08e12770722bf780a' 
  AND token = 'HLWnJtD/CON4G0k5/6z4zVO+BFBHefDnBsQCETPOF5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}