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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad243d009b684cf6c9242ad33aabd8021062270904425b81bc2107606be44765' 
  AND token = 'XVELWMq6vQTUq8Us3Cc0LseerYRhhfOKpfSG57UwSS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00108

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}