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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59239bbdf7638415cb249d75b44008166dc4bd82e56b49116c553620e41ac8fd' 
  AND token = '2LE2b9YHS65Nqf4l86aEW9xX8d7vGlF/WxKf1wkZfmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}