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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a801b0c5414a636258c8af64f67a813f7309eefab727f6bec4a63e5ffbb56b' 
  AND token = 'ISY40pRXRq1H5r1zrKXfkdfti+sFRIY9bMIl6gKq4fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}