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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8da8831bf0dd914db5ffb690458c282ac0c7603ce0dcbf2674456f127cffe627' 
  AND token = '8zDm0G7eEe92t12vVhON1WssvhIodSpIeB/TdeO38eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}