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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dddc97efee3ec2db389bdd81b6c97e82a21598bf3098c1af46ea747c24b515a' 
  AND token = '+LuKZqJomc+nsNRI2ROaA0uaVVpYV4mT3p65+Mwo1pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}