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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '579f71499d4539ba748f4846d215a9d1eccafafd0fc7fba02ff971f8f3a5d766' 
  AND token = 'gwSrEARgZnJLHac2AgZKJn7Ycg3SpKVmVAfi7zMd6hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}