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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5434719273206e4b2a015f63a31d9f1b8cac825435957896e433b9a934b428aa' 
  AND token = '1kygEZDDO6rmXOBNErr547JMz3Z29ZRRtwb+f77pgno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}