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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf6e4c49b335623aafd04a2f84e20ffd957db678bb26185d0d708e194f3b35b' 
  AND token = 'KV9IajIEoSpIi4AtM/TI+pBI3h/RF4832LcjvfF6bf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}