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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b7c3fe8481924f275fd1f265f0c06b81cc216a5a30d72c3f6b6a50791f7a0df' 
  AND token = 'YKCVugnnKty7oEUw9I3u0wuGv+R+rO4R3E5KWuAkuD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}