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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6443150d54f46aa03b3602685aa626a720941a535e717978a75702a9844e87c' 
  AND token = 'tOB8krL3YPXFIFTLok8CjWlO+65mh8nomSVPkKiqY2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}