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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164e0fc903f29d8e9a0139ef2e659b70add995546299862679e5cfa99c564e65' 
  AND token = 'AjiaVk1+LTDx3lpxGQrzVrQCUC8MrHHLgXTPN+6Ul7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}