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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff169b3974874b6cf6e247d9ec84eda6ccff046e3e23c977e8ee8205e2efe68' 
  AND token = 'UEcagVTEkKYnRu+rptt56gitnh/vU3nkB6tYVYM5GsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}