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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0a3e6a5b9aefdfba22441907c3b0a06b8201592e3bed011c1c22c6dbff460c7' 
  AND token = 'Ox5WicZVK9cJ60T7edcU9NyMwj+vfiE8GfgmhMO9E7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}