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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b5967fd04ab55e6cb020fb42145c7a37327508274e127b8a1a9d4c436cb275e' 
  AND token = 'TYfL73FhF80DTE5dF2NWlmDd0v2dgRdHzzWuGQ4RAxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}