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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa7412bfabdddaf9d57e63eeac8087ee97fa72a962be726f139e62723c43a582' 
  AND token = 'PqJ6eSyrSDvBXY+t8cZM8d8vglX6vgWgn3gyVl0UpQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}