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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48866f826dc9826e1735694b274f10acd949f279379bfa53e381e9c4662b9462' 
  AND token = 'IL4VvEJ63sW6IG78ar3sjHeuVw4+Plb9DSukk+jvwKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}