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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d7183552df359b978329cbffab39f082d3a6a8138123136e36f90c4867face' 
  AND token = 'nhaheAjoBuUZ2ecgg0JHowEAtdmqtMVFUGaT2XPX3i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}