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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ae01a5abc7b1250cdb89b6f6be2194b504471273b4e9ca78b1991121885b1a' 
  AND token = '24DFr2omMfLZFJ2YT+Qpsk0oJ8TDjdcZVTh5nrU5gGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}