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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5c4a41a3e0bb53a0e06ad000ae4ac26d81d86985b592d7ba251032233a72817' 
  AND token = 'zJnUBzcYz2DYlEqVOlp4CM2fFycTpbvqKOuWAL6IL/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}