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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b11b42770c283cf528b94586117f325c760211f16046321224e9d1a84db4dec' 
  AND token = 'SF3kHnMhtUNdWqryGtOL+ZHDTKTC1af/7xwEPU3kd+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}