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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3218f4ce2e29eaf62dce1c1ec04eed466593dec5b74d7843329227a78af4f360' 
  AND token = 'yuAGNAHHJy29h9Ra3Z3uyMsYnB3Np6a2iHoJY+pfAEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}