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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c21f30604f2398b8220b4b400d5a90fad182845a60a3ebc75e2b250ae7a2fc5' 
  AND token = 'aeL/NSlR8izuhKfvyyuJ64QQ5+bPTvme/zE5YYzNO1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}