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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49ef6ccd40bced008567bc519df3bd48bfc780a6957a368d43c461eb256b432' 
  AND token = 'prdh14i6mPBA5Q/lcGwyN1ZFWmyX8o/VjjBCzl76D7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}