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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a0648572847164a236343fcfc9255ca60ff17d378e7bd33fca5a19f57bc8131' 
  AND token = '1xA+DpEoArVTqEJbTXvYp9cZiWMV4umb2iLCnz3504E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}