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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04da4d1639623bc58a2bd12ac3930c8cf6cbf2b9e2a6e1d8deb848abddca7c61' 
  AND token = 'TEkZqn1g0KVzp8FE5dCUD0/I5teM1vQBKbdAvu2gtEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}