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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49de4316751d750747c0dd9f6b94c7b027177e95d76c3017cb9759b209a9bfa' 
  AND token = 'tPErEflvOhy3AUvJp01a9+cH9ReohJTPFjwNPIOA/Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}