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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8878a16d88f2d99bad7bd58ba49265bd056b374af01aa74e709bd0dafbbf2c' 
  AND token = 'nEZ8l0mqECCIijkCKg8VJxz1fFMhEXEccuYQjpsOMRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}