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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '502af2483393b77c5f3628fe9a91a7290e6b06cfa1ac961090fcb9400ce62aff' 
  AND token = 'DPfdgOg/9Gzkf00n30GrHpehSsRxp6ogGst4NT2FY5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}