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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e0c72f280112f68336965a316ca58b2ba32e72ff5b762dc7157c21d3da6d00' 
  AND token = 'W6QTDrpBCFeGaiHHzDo9oaWr1z5bONe7cubxoMWbT10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}