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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e572355668220041c426eecf68e09ef2d66c673959393bbe26a22b92f77e916' 
  AND token = 'o0dgx4hYlQCPm1/jFubeiUZM7CZOuy9UDSsUrs22Gvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}