SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    4651, 5190, 1580, 3324, 3495, 5253, 5387, 
    3321, 3327, 1667, 3932, 2090, 2277, 
    5843, 2278, 5969, 3338, 2400, 5814, 
    5251, 5831, 4239, 5751, 5740, 4191, 
    5839, 2179, 5813, 1629, 5205, 5266, 
    1666, 5024, 5262, 5282, 5565, 3332, 
    5275, 5264, 5825, 5924, 5283, 5838, 
    5268, 5738, 1630, 3494, 5274, 2183, 
    2237, 5273, 5291, 2087, 3491, 3930, 
    4233, 5927, 2239, 8813, 1843, 5182, 
    2092, 5267, 5279, 2176, 2238, 5269, 
    5280, 5017, 1671, 3801, 2091, 1845, 
    2089, 3498, 5286, 2276, 4475, 3506, 
    5211
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00202

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "56.01"
    },
    "grouping_operation": {
      "using_filesort": false,
      "table": {
        "table_name": "cscart_product_prices",
        "access_type": "range",
        "possible_keys": [
          "usergroup",
          "product_id",
          "lower_limit",
          "usergroup_id"
        ],
        "key": "product_id",
        "used_key_parts": [
          "product_id"
        ],
        "key_length": "3",
        "rows_examined_per_scan": 80,
        "rows_produced_per_join": 15,
        "filtered": "19.99",
        "index_condition": "(`softwarepirmam_hewadelivard_cscart_4`.`cscart_product_prices`.`product_id` in (4651,5190,1580,3324,3495,5253,5387,3321,3327,1667,3932,2090,2277,5843,2278,5969,3338,2400,5814,5251,5831,4239,5751,5740,4191,5839,2179,5813,1629,5205,5266,1666,5024,5262,5282,5565,3332,5275,5264,5825,5924,5283,5838,5268,5738,1630,3494,5274,2183,2237,5273,5291,2087,3491,3930,4233,5927,2239,8813,1843,5182,2092,5267,5279,2176,2238,5269,5280,5017,1671,3801,2091,1845,2089,3498,5286,2276,4475,3506,5211))",
        "cost_info": {
          "read_cost": "54.41",
          "eval_cost": "1.60",
          "prefix_cost": "56.01",
          "data_read_per_join": "383"
        },
        "used_columns": [
          "product_id",
          "price",
          "percentage_discount",
          "lower_limit",
          "usergroup_id"
        ],
        "attached_condition": "((`softwarepirmam_hewadelivard_cscart_4`.`cscart_product_prices`.`lower_limit` = 1) and (`softwarepirmam_hewadelivard_cscart_4`.`cscart_product_prices`.`usergroup_id` in (0,1)))"
      }
    }
  }
}