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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5f2cf729e973b4ad2a7963adbfeceb16942d42895d49d6b631acf1daf994b19' 
  AND token = '3bNf7Q4o+QaFgElJG0c6BJtOjOtKJEVyji09eMovB1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}